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Signalling and Acquired Resistance to Targeted Cancer Therapeutics

Signalling and Acquired Resistance to Targeted Cancer Therapeutics

Bluepharma/University of Coimbra Innovation Award

The Bluepharma | University of Coimbra Innovation Award is attributed every 2 years to an innovative research project in the health area. All research labs, institutes and organizations that host innovative research projects involving Portuguese researchers may apply.

 

These projects may be carried out by groups of more than one institution, but the research work must have been partially or totally conducted in Portuguese institutions, by Portuguese and/or foreign researchers.

 

Bluepharma/University of Coimbra Innovation Award

The Bluepharma | University of Coimbra Innovation Award is attributed every 2 years to an innovative research project in the health area. All research labs, institutes and organizations that host innovative research projects involving Portuguese researchers may apply.

 

These projects may be carried out by groups of more than one institution, but the research work must have been partially or totally conducted in Portuguese institutions, by Portuguese and/or foreign researchers.

 

Regulation of histone H2A.Z expression is mediated by SIRT1 in prostate cancer


Tiago Baptista1,2, Inês Graça1,2,4, Elsa J. Sousa1,2, Ana I. Oliveira1,2, Natália R. Costa1,2, Pedro Costa-Pinheiro1,2, Francisco Amado5, Rui Henrique1,3,6 and Carmen Jerónimo1,2,6

1Cancer Epigenetics Group, Research Center, Portuguese Oncology Institute – Porto, Portugal

2Department of Genetics, Portuguese Oncology Institute – Porto, Portugal

3Department of Pathology, Portuguese Oncology Institute – Porto, Portugal

Regulação da expressão da histona H2A.Z é mediada pelo SIRT1 no cancro da próstata

Dentro dos mecanismos clássicos de carácter epigénetico associado à carcinogénese, aqueles que dizem respeito às alterações de variantes de histonas são os menos compreendidos. Contudo, nos últimos anos, a variante H2A.Z e a sua forma acetilada têm surgido como um elemento importante no desenvolvimento e progressão neoplásica, nomeadamente em cancro da mama e da próstata, tendo sido sugeridas como alvos terapêuticos em carcinoma mamário.

Genomic study of gastric cancer involving a portuguese-chinese consortium

The Coimbra Genomics S.A., a company dedicated to the emergent field of genomics, jointly with IPATIMUP and the Chinese organization BGI are lauching a research project aiming to understand the genetic basis of gastric carcinoma.

Estudo de genómica de cancro do estômago envolvendo consórcio luso-chinês

A empresa Coimbra Genomics S.A., dedicada ao emergente campo da genómica, em conjunto com o IPATIMUP e a organização chinesa BGI (antigo Beijing Genomics Institute), vão avançar com um projeto de investigação cujo fim é a compreensão das bases genéticas do cancro do estômago.
  

ISREC Symposium: Metastatic colonization: micro-environments, mechanisms and therapeutic targeting

Crans Montana, Switzerland

 

22-25 January, 2014

 

See more informations here: http://isrec2014.epfl.ch/

ISREC Symposium: Metastatic colonization: micro-environments, mechanisms and therapeutic targeting

Crans Montana, Switzerland

 

22-25 January, 2014

 

See more informations here: http://isrec2014.epfl.ch/