Anticancer compound

send to a friend share this

Aptamer-based targeted Delivery of a G-quadruplex Ligand in Cervical Cancer Cell

<Back to list

In this work, the team led by Carla Cruz from the Health Sciences Research Centre of the University of Beira Interior (CICS-UBI) has developed a strategy for the selective delivery of an anticancer compound to cervical cancer cells, using AS1411 as vehicle. AS1411 aptamer is a guanine-rich oligonucleotide which binds and recognizes protein nucleolin that is overexpressed on the surface of cancer cells, showing anticancer activity on a variety of cancer cell types.

Tags: 
Targeted Delivery
Cervical Cancer Cell
Anticancer compound
Carla Cruz
Josué Carvalho
ASPIC

Anticancer compound found in cyanobacteria from the portuguese coast

<Back to list

Authors:

Pedro N Leão, Margarida Costa, Vitor Ramos, Alban R Pereira, Virgínia C Fernandes, Valentina F Domingues, William H Gerwick, Vitor M Vasconcelos, Rosário Martins
 
Affiliations:
Pedro N. Leão, Margarida Costa, Vitor Ramos, Vitor M. Vasconcelos, Rosário Martins

- CIIMAR – Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto

Pedro N. Leão, Alban R. Pereira, William H. Gerwick

Tags: 
Anticancer compound
cyanobacteria
hierridina B
Aguda beach
Pedro N Leão
Rosário Martins
ASPIC

Partners